If you ran evolution all over again, would you get humans? How repeatable is #evolution? This video is sponsored by @BountyBrand. #biology #science #QPU #HygieneBeginswithBounty #BountyPartner

Special thanks to Prof. Richard Lenski and team for showing me around the lab — it is an honor to be able to witness and document such a historic science experiment.

Thanks to Dr Zachary Blount for the help with research and setting up the competition time-lapse, Dr Nkrumah Grant for microscope images of the long-term line cells @NkrumahGrant

Devin Lake, Kate Bellgowan, and Dr. Minako Izutsu for being part of this video. Long Live the LTEE!

LTEE website — http://myxo.css.msu.edu/ecoli/index.html

Intro footage courtesy of the Kishony Lab — https://kishony.technion.ac.il

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References:

Lenski, R. E., & Travisano, M. (1994). Dynamics of adaptation and diversification: a 10,000-generation experiment with bacterial populations. Proceedings of the National Academy of Sciences, 91(15), 6808-6814. — https://ve42.co/Lenski1994

Lenski, R. E., Rose, M. R., Simpson, S. C., & Tadler, S. C. (1991). Long-term experimental evolution in Escherichia coli. I. Adaptation and divergence during 2,000 generations. The American Naturalist, 138(6), 1315-1341. — https://ve42.co/Lenski1991

Good, B. H., McDonald, M. J., Barrick, J. E., Lenski, R. E., & Desai, M. M. (2017). The dynamics of molecular evolution over 60,000 generations. Nature, 551(7678), 45-50. — https://ve42.co/Good2017

Blount, Z. D., Borland, C. Z., & Lenski, R. E. (2008). Historical contingency and the evolution of a key innovation in an experimental population of Escherichia coli. Proceedings of the National Academy of Sciences, 105(23), 7899-7906. — https://ve42.co/Blount2008

Blount, Z. D., Lenski, R. E., & Losos, J. B. (2018). Contingency and determinism in evolution: Replaying life’s tape. Science, 362(6415). — https://ve42.co/Blount2018

Wiser, M. J., Ribeck, N., & Lenski, R. E. (2013). Long-term dynamics of adaptation in asexual populations. Science, 342(6164), 1364-1367. — https://ve42.co/Wiser2013

N, Scharping. (2019). How a 30-Year Experiment Has Fundamentally Changed Our View of How Evolution Works. Discover — https://ve42.co/Scharping

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Special thanks to Patreon supporters: Mike Tung, Evgeny Skvortsov, Meekay, Ismail Öncü Usta, Paul Peijzel, Crated Comments, Anna, Mac Malkawi, Michael Schneider, Oleksii Leonov, Jim Osmun, Tyson McDowell, Ludovic Robillard, Jim buckmaster, fanime96, Juan Benet, Ruslan Khroma, Robert Blum, Richard Sundvall, Lee Redden, Vincent, Marinus Kuivenhoven, Alfred Wallace, Arjun Chakroborty, Joar Wandborg, Clayton Greenwell, Pindex, Michael Krugman, Cy 'kkm' K'Nelson, Sam Lutfi, Ron Neal

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Research and Writing by by Derek Muller, Petr Lebedev and Casey Rentz

Animation by Iván Tello

Filmed by Derek Muller, Emily Zhang and Raquel Nuno

Edited by Derek Muller

Music by Jonny Hyman and from Epidemic Sound https://epidemicsound.com

Additional video supplied by Getty Images

Thumbnail image courtesy of the Kishony Lab

Produced by Casey Rentz

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